A new study has found that women produce a more powerful immune response than men do. While coronavirus may infect anyone, young or old, older men are up to twice as likely to become severely sick and to die as women of the same age.
According to a new study, men produce a weaker immune response to the virus than women do, the researchers concluded.
The findings, published on Wednesday in a Nature magazine, suggest that men, particularly those over age 60, may need to depend more on vaccines to protect themselves against the infection.
Natural infection is clearly failing “to spark adequate immune responses in men”, said Akiko Iwasaki, an immunologist at Yale University who led the work.
Results on sex differences reveal that women mount faster and stronger immune responses, perhaps because their bodies are rigged to fight pathogens that threaten unborn or newborn children.
Dr. Marcus Altfeld, an immunologist at the Heinrich Pette Institute notes that companies pursuing coronavirus vaccines may need to parse their data by sex. This may influence their decisions about dosing.
“You could imagine scenarios where a single shot of a vaccine might be sufficient in young individuals or maybe young women, while older men might need to have three shots of vaccine,” Dr. Altfeld said.